
Ipamorelin
Selective Growth Hormone Secretagogue (GHRP)
Ipamorelin is a selective growth hormone releasing peptide (GHRP) that specifically stimulates the release of growth hormone without affecting other hormones. Unlike other GHRPs, Ipamorelin does not increase cortisol, acetylcholine, prolactin, or aldosterone levels, making it the most selective and well-tolerated growth hormone secretagogue available for research and therapeutic applications.
Clinical Benefits
Mechanism of Action
Ipamorelin acts as a selective agonist of the growth hormone secretagogue receptor (GHSR-1a) located in the anterior pituitary gland. Upon binding, it stimulates the release of growth hormone through a G-protein coupled receptor mechanism, specifically activating the GHS-R1a subtype. Unlike other growth hormone releasing peptides, Ipamorelin demonstrates remarkable selectivity, stimulating GH release without affecting the secretion of ACTH, cortisol, prolactin, FSH, LH, or TSH. This selective action is attributed to its specific receptor binding profile and downstream signaling cascade.
Proven Results
Medical Disclaimer
Ipamorelin is currently in research phase and is not FDA-approved for human therapeutic use. This information is for educational purposes only and should not replace consultation with healthcare providers. Individual results may vary. Medical supervision is recommended for all research applications.