HGH
Human Growth Hormone (Somatropin)
Human Growth Hormone (HGH), also known as somatropin when manufactured recombinantly, is a critical anabolic hormone that stimulates growth, cellular regeneration, and metabolism. FDA-approved for growth hormone deficiency in children and adults, Turner syndrome, and other growth disorders. HGH promotes lean muscle mass, reduces body fat, improves bone density, and enhances overall quality of life through its primary mediator, insulin-like growth factor-1 (IGF-1).
Clinical Benefits
Mechanism of Action
Human Growth Hormone exerts its effects by binding to growth hormone receptors (GHR) throughout the body, particularly in liver, muscle, bone, and adipose tissue. This binding activates the JAK2-STAT5 signaling pathway, leading to increased transcription of IGF-1 and other growth-promoting genes. IGF-1, produced primarily in the liver, mediates most of HGH's anabolic effects through IGF-1 receptors, promoting protein synthesis, cellular proliferation, and tissue growth while enhancing lipolysis and glucose metabolism.
Proven Results
Medical Disclaimer
Human Growth Hormone (HGH/Somatropin) is FDA-approved for growth hormone deficiency and specific medical conditions. This information is for educational purposes and should not replace consultation with qualified healthcare providers. HGH requires prescription and medical supervision for all therapeutic uses. Individual results may vary based on baseline hormone levels and clinical status.