
Max Weight Loss20.9%
Studies12
Participants8,750
StatusAvailable
Tirzepatide
Dual GIP and GLP-1 Receptor Agonist
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Available as FDA-approved Mounjaro® for Type 2 diabetes and Zepbound® for weight management and obstructive sleep apnea. It provides superior weight loss and glycemic control compared to single-pathway medications through its unique dual mechanism of action.
Evidence-Based Combination Strategies
Tirzepatide + Lifestyle Intervention
Evidence-BasedEvidence Base:
SURMOUNT trial lifestyle components
N = 2,539 participants
Clinical Outcomes:
Enhanced weight loss maintenance with structured behavioral support
Safety Profile:
Excellent safety profile with comprehensive lifestyle program
Implementation Protocol:
Weekly injections + caloric restriction + exercise program + behavioral counseling
Medical Disclaimer
Tirzepatide is FDA-approved as Mounjaro® for Type 2 diabetes and Zepbound® for chronic weight management. This information is for educational purposes and should not replace consultation with healthcare providers. Individual results may vary. Prescribing information and medical supervision are required for all therapeutic uses.