Eagle LogoPEPTIDE INITIATIVE

Peptide Database

Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
Cagrilintide
Weight Management
CJC-1295
Growth Hormone
DSIP
Sleep & Recovery
Epithalon
Anti-Aging
GHK-Cu
Anti-Aging
GHRP-2
Growth Hormone
HCG
Hormone Support
Hexarelin
Growth Hormone
HGH
Growth Hormone
IGF-1 LR3
Growth Hormone
Kisspeptin
Hormone Support
Melanotan-2
Cosmetic
MOTS-C
Metabolic
NAD+
Anti-Aging
Oxytocin Acetate
Hormone Support
PEG-MGF
Recovery
PT-141
Sexual Health
Retatrutide
Weight Management
Selank
Cognitive
Semaglutide
Weight Management
Semax
Cognitive
Sermorelin
Growth Hormone
Snap-8
Cosmetic
SS-31
Mitochondrial
TB-500
Healing & Recovery
Tesamorelin
Growth Hormone
Thymosin Alpha-1
Immune
Tirzepatide
Weight Management
Total Peptides: 31
Back to Home
Retatrutide
EfficacyHigh
Studies8
Participants6,200
StatusAvailable

Retatrutide

LY3437943

Retatrutide is a novel triple hormone receptor agonist that simultaneously activates GLP-1, GIP, and glucagon receptors for superior metabolic effects. This innovative approach produces enhanced appetite suppression, improved insulin sensitivity, and increased energy expenditure, potentially delivering 20-25% weight loss in clinical trials.

Complete Dosing Guide

Quick Reference

2.4-12
Typical Dose
Weekly
Frequency
5-7
Half-Life
SubQ
Route

Administration Method

Subcutaneous injection once weekly

Step-by-Step Dosing Protocol

Initial
2.4-12 mg weekly
Getting started
Follow gradual escalation approach
Maintenance
Optimized dose
Sustained benefits
Continue at effective dose
Cycling
Break period
Recovery
Take breaks to maintain effectiveness

Dosing Guidelines

Research Protocol

Standard escalation begins with 2.4 mg weekly for 4 weeks, followed by 4.8 mg weekly for 4 weeks. Further increases to 7.2 mg and maximum 12 mg weekly should occur at 4-week intervals based on clinical response and tolerability. Most patients achieve optimal results at 7.2-12 mg weekly for weight management.

Simple Explanation

You always start low and go slow with Retatrutide. Everyone starts with 2.4mg once a week for a month. Then you increase by 2.4mg every month until you find the dose that works best for you, up to 12mg per week maximum. Most people end up taking 7.2-12mg per week for the best weight loss results.

Mixing & Injection

Technical Instructions

Subcutaneous injection using pre-filled pens or vials with separate syringes. Injection sites include abdomen, thigh, or upper arm. Rotate injection sites weekly to prevent lipodystrophy. Administer on the same day each week, any time of day, with or without meals. If dose is missed, administer as soon as possible if within 4 days, otherwise skip and resume regular schedule.

Step-by-Step Guide

Subcutaneous injection using pre-filled pens or vials with separate syringes. Injection sites include abdomen, thigh, or upper arm. Rotate injection sites weekly to prevent lipodystrophy. Administer on the same day each week, any time of day, with or without meals. If dose is missed, administer as soon as possible if within 4 days, otherwise skip and resume regular schedule.

Clinical Administration Guidelines

Injection Protocol

  • Subcutaneous injection per protocol
  • Rotate injection sites
  • Consistent daily timing
  • Follow protocol guidelines

Monitoring Schedule

  • Regular progress monitoring
  • Health parameter monitoring
  • Laboratory monitoring
  • Safety monitoring

Dosage Calculator

Loading Calculator...

Medical Disclaimer

Retatrutide is currently in Phase 3 clinical trials and is not yet FDA approved. This information is for educational purposes only and should not replace medical advice. Consult with healthcare providers familiar with investigational therapies for personalized guidance. Side effects and contraindications are based on available clinical trial data.