EfficacyHigh
Studies8
Participants6,200
StatusAvailable
Retatrutide
LY3437943
Retatrutide is a novel triple hormone receptor agonist that simultaneously activates GLP-1, GIP, and glucagon receptors for superior metabolic effects. This innovative approach produces enhanced appetite suppression, improved insulin sensitivity, and increased energy expenditure, potentially delivering 20-25% weight loss in clinical trials.
Daily Implementation Guide
Daily Implementation Schedule
Lifestyle Integration Strategies
Nutrition Optimization
- •High-protein meals (30-40g per meal)
- •Eat slowly to enhance satiety effects
- •Stay hydrated (3+ liters daily)
- •Avoid high-fat meals on injection day
Exercise Enhancement
- •Start with 150 min moderate exercise weekly
- •Resistance training 2-3x per week
- •Monitor energy levels during escalation
- •Adjust intensity based on side effects
Sleep & Recovery
- •Maintain consistent sleep schedule
- •Monitor for sleep quality improvements
- •Track energy levels throughout day
- •Adjust injection timing if affecting sleep
Progress Tracking
Weekly Weight
Track: Every Monday AM
Target: 1-2 lbs/week loss
Waist Circumference
Track: Monthly
Target: 2-4 inches reduction
Energy Levels
Track: Daily (1-10 scale)
Target: Gradual improvement
Side Effects
Track: Daily
Target: Decrease over time
HbA1c (if diabetic)
Track: Every 3 months
Target: <7% or per doctor
SUCCESS MILESTONES
5% weight loss8-12 weeks
10% weight loss16-24 weeks
15% weight loss32-48 weeks
20%+ weight loss52-72 weeks
Medical Disclaimer
Retatrutide is currently in Phase 3 clinical trials and is not yet FDA approved. This information is for educational purposes only and should not replace medical advice. Consult with healthcare providers familiar with investigational therapies for personalized guidance. Side effects and contraindications are based on available clinical trial data.