
Oxytocin Acetate
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂
Oxytocin Acetate is a synthetic form of the naturally occurring neuropeptide hormone oxytocin. FDA-approved for obstetric uses including labor induction, augmentation, and postpartum hemorrhage prevention. In research settings, it shows promise for treating autism spectrum disorders and enhancing social cognition through its effects on oxytocin receptors in the brain and peripheral tissues.
Complete Research Database
Dual Receptor Mechanism (GIP/GLP-1)
GLP-1 Receptor Pathway
- •Increases insulin secretion (glucose-dependent)
- •Suppresses glucagon release
- •Slows gastric emptying
- •Enhances satiety in hypothalamus
- •Preserves beta-cell function
GIP Receptor Pathway
- •Enhances insulin secretion (stronger than GLP-1)
- •Promotes fat oxidation
- •Improves insulin sensitivity in muscle
- •Reduces hepatic glucose production
- •Modulates adipose tissue metabolism
Why Dual Agonism is Superior
Oxytocin Acetate binds to oxytocin receptors (OXTR), which are G-protein coupled receptors located in uterine myometrium, mammary glands, and central nervous system. Receptor activation triggers phospholipase C activation, leading to increased intracellular calcium levels and smooth muscle contraction. In the CNS, oxytocin modulates neurotransmitter release affecting social behavior, stress response, and maternal bonding through hypothalamic-pituitary pathways.
Pharmacokinetic Profile
Top 10 High-Quality Research Articles
WHO Labour Care Guide: Evidence-based recommendations for intrapartum care
ReadPrevention of postpartum haemorrhage with oxytocin ten units
ReadIntranasal oxytocin in autism spectrum disorder: systematic review
ReadOxytocin for labour induction in women with a previous caesarean section
ReadMaternal and neonatal effects of oxytocin infusion during labour
ReadMedical Disclaimer
Oxytocin Acetate is FDA-approved for obstetric uses and requires medical supervision. This information is for educational purposes and should not replace consultation with healthcare providers. Individual results may vary. Proper monitoring is essential during all clinical applications.