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Peptide Database

Adipotide
Weight Management
AOD-9604
Weight Management
BPC-157
Healing & Recovery
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Weight Management
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Growth Hormone
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Tirzepatide
Weight Management
Total Peptides: 31
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Melanotan-2
Tanning Effect85%
Studies4
Participants33
StatusOut of Stock

Melanotan-2

MT-II, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

Melanotan-2 (MT-II) is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a non-selective melanocortin receptor agonist. Originally developed for skin pigmentation research, it has also been investigated for erectile dysfunction. NOT FDA approved and carries significant safety warnings from health agencies worldwide due to serious adverse effects including potential melanoma risk.

Clinical Safety Profile

Reported Side Effects

Nausea (most common, reported in majority of users)
Facial flushing and skin irritation
Spontaneous penile erections (males)
Decreased appetite and food aversion
Fatigue and somnolence
Vomiting at higher doses
Darkening of existing moles and freckles
Development of new pigmented nevi

Side Effect Management (Clinical Trial Data)

Nausea
Common
68%
Facial Flushing
Common
45.2%
Spontaneous Erections
Common
85%
Decreased Appetite
Common
32.1%
Fatigue
Common
28.6%

Side Effect Management Strategies

Nausea: Take with food, smaller meals, ginger supplements
Vomiting: Slower dose escalation, anti-emetics if severe
Diarrhea: Adequate hydration, probiotics, bland diet
Constipation: Increase fiber intake, adequate fluids, light exercise

Clinical Safety Metrics

Poor
Overall Safety Rating
68%
Trial Termination Rate
PROHIBITED
Development Status

CONTRAINDICATIONS

• NOT FDA approved - use prohibited
• Personal or family history of melanoma
• Predisposition to skin cancer
• History of cardiac arrhythmias

Medical Disclaimer

CRITICAL WARNING: Melanotan-2 is NOT approved by the FDA or any major regulatory agency for human use. Health authorities worldwide have issued warnings against its use due to serious safety risks including potential melanoma, priapism, rhabdomyolysis, and systemic toxicity. This information is for educational and research purposes only. Any use requires medical supervision and carries significant legal and health risks. Consult healthcare providers for approved alternatives.