EfficacyHigh

Studies15

Participants69,017

StatusAvailable

HGH

Human Growth Hormone (Somatropin)

Human Growth Hormone (HGH), also known as somatropin when manufactured recombinantly, is a critical anabolic hormone that stimulates growth, cellular regeneration, and metabolism. FDA-approved for growth hormone deficiency in children and adults, Turner syndrome, and other growth disorders. HGH promotes lean muscle mass, reduces body fat, improves bone density, and enhances overall quality of life through its primary mediator, insulin-like growth factor-1 (IGF-1).

Clinical Safety Profile

Reported Side Effects

Joint pain and stiffness (most common)

Peripheral edema (fluid retention)

Muscle pain and weakness

Carpal tunnel syndrome

Increased insulin resistance

Injection site reactions

Headache and fatigue

Numbness and tingling

Side Effect Management (Clinical Trial Data)

Joint Pain

Common

18.2%

Peripheral Edema

Occasional

13.7%

Muscle Pain

Occasional

11.4%

Carpal Tunnel

Infrequent

7.8%

Injection Site Reactions

Infrequent

6.2%

Side Effect Management Strategies

Nausea: Take with food, smaller meals, ginger supplements

Vomiting: Slower dose escalation, anti-emetics if severe

Diarrhea: Adequate hydration, probiotics, bland diet

Constipation: Increase fiber intake, adequate fluids, light exercise

Clinical Safety Metrics

Variable

Overall Safety Rating

Variable

Discontinuation Rate

Research

Approved Status

CONTRAINDICATIONS

• Active malignancy or cancer history

• Diabetic retinopathy (proliferative or severe)

• Critical illness or acute respiratory failure

• Known hypersensitivity to somatropin

Medical Disclaimer

Human Growth Hormone (HGH/Somatropin) is FDA-approved for growth hormone deficiency and specific medical conditions. This information is for educational purposes and should not replace consultation with qualified healthcare providers. HGH requires prescription and medical supervision for all therapeutic uses. Individual results may vary based on baseline hormone levels and clinical status.

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