Hexarelin

His-D-Trp-Ala-Trp-D-Phe-Lys-NH2

Hexarelin is a synthetic hexapeptide belonging to the growth hormone releasing peptide (GHRP) family and is recognized as one of the most potent growth hormone secretagogues available. It binds to ghrelin receptors (GHS-R) in the hypothalamus and pituitary gland, triggering powerful growth hormone release and providing unique cardiovascular protective benefits beyond other GHRPs.

Clinical Safety Profile

Reported Side Effects

Mild injection site irritation or redness

Temporary increased hunger (ghrelin receptor activation)

Mild water retention or bloating

Transient fatigue during initial adaptation

Possible mild hypoglycemia in sensitive individuals

Temporary joint discomfort during muscle growth phase

Sleep pattern changes during adjustment period

Side Effect Management (Clinical Trial Data)

Side Effect Management Strategies

Nausea: Take with food, smaller meals, ginger supplements

Vomiting: Slower dose escalation, anti-emetics if severe

Diarrhea: Adequate hydration, probiotics, bland diet

Constipation: Increase fiber intake, adequate fluids, light exercise

Clinical Safety Metrics

Variable

Overall Safety Rating

Variable

Discontinuation Rate

Research

Approved Status

CONTRAINDICATIONS

• Active cancer or history of malignancy (growth hormone sensitive)

• Severe cardiac arrhythmias or unstable heart conditions

• Uncontrolled diabetes or severe hypoglycemia

• Pregnancy or breastfeeding

Medical Disclaimer

Hexarelin is a research chemical not approved by the FDA for human use. This information is for educational purposes only and should not replace professional medical advice. Always consult with a qualified healthcare provider before starting any peptide therapy. Individual results may vary. Not suitable for use by minors, pregnant or nursing women, or individuals with certain medical conditions.

Peptide Database