HCG
Human Chorionic Gonadotropin
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced during pregnancy that mimics luteinizing hormone (LH) activity. It's FDA-approved for fertility treatments and hypogonadism in men. HCG stimulates testosterone production in males and triggers ovulation in females, making it valuable for hormone support, fertility preservation during testosterone therapy, and reproductive treatments.
Complete Dosing Guide
Quick Reference
Administration Method
Subcutaneous or intramuscular injection
Step-by-Step Dosing Protocol
Dosing Guidelines
For male hypogonadism and fertility preservation: 1,000-2,500 IU administered 2-3 times weekly via subcutaneous injection. For female ovulation induction: single intramuscular injection of 5,000-10,000 IU administered 34-38 hours after last FSH injection. For maintenance during TRT: 250-500 IU twice weekly subcutaneously. Duration varies from single doses for ovulation to ongoing therapy for testosterone support. Dosing should be individualized based on hormone monitoring and clinical response.
For men who need testosterone support, the typical dose is 250-500 IU injected under the skin twice a week, ongoing with testosterone therapy. For women in fertility treatments, it's usually one bigger shot of 5,000-10,000 IU into the muscle to trigger egg release. Men using it for fertility preservation typically get 1,000-2,500 IU 2-3 times per week. Your doctor will adjust the dose based on your hormone levels and how you respond.
Mixing & Injection
HCG is administered via subcutaneous injection using insulin syringes for smaller doses (250-500 IU) or intramuscular injection for larger doses (>1,000 IU). Subcutaneous sites include abdomen, thigh, or upper arm, rotated to prevent lipodystrophy. Intramuscular administration uses larger needles in the gluteal or deltoid muscle. Reconstitution requires bacteriostatic water, typically at concentrations of 1,000-5,000 IU/mL. Timing is critical - evening administration is preferred for men to mimic natural LH rhythms.
HCG is administered via subcutaneous injection using insulin syringes for smaller doses (250-500 IU) or intramuscular injection for larger doses (>1,000 IU). Subcutaneous sites include abdomen, thigh, or upper arm, rotated to prevent lipodystrophy. Intramuscular administration uses larger needles in the gluteal or deltoid muscle. Reconstitution requires bacteriostatic water, typically at concentrations of 1,000-5,000 IU/mL. Timing is critical - evening administration is preferred for men to mimic natural LH rhythms.
Clinical Administration Guidelines
Injection Protocol
- •Subcutaneous injection twice weekly
- •Rotate between abdomen, thigh, upper arm
- •Twice weekly with TRT schedule
- •Can be taken with or without food
Monitoring Schedule
- •Weekly testosterone and fertility markers
- •Quarterly fertility and hormone panels
- •Regular testosterone and fertility monitoring
- •STOP if mood changes or cardiovascular symptoms
Dosage Calculator
Medical Disclaimer
HCG is FDA-approved for specific fertility indications and testosterone replacement therapy support. This information is for educational purposes only and should not replace consultation with healthcare providers. Use only under medical supervision with appropriate monitoring.