GHRP-2
D-alanyl-D-2-naphthylalanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide developed as a second-generation growth hormone secretagogue by Bowers and colleagues in the early 1990s. Also known as pralmorelin in clinical literature, it potently stimulates growth hormone release through GHS-R1a receptor activation. GHRP-2 incorporates D-amino acids for enhanced stability and resistance to enzymatic degradation, making it significantly more potent than earlier analogs like GHRP-6.
Complete Dosing Guide
Quick Reference
Administration Method
Subcutaneous injection, typically before meals or bedtime
Step-by-Step Dosing Protocol
Dosing Guidelines
Research protocols typically employ 100-300 mcg daily doses, administered subcutaneously. The optimal protocol involves 2-3 daily injections: 100 mcg upon waking (fasted state), 100 mcg pre-workout or mid-afternoon, and 100-200 mcg before bedtime. Clinical studies used single 1 µg/kg IV doses (approximately 70-100 mcg for average adults). Animal studies suggest saturation occurs around 1 mg/kg, indicating diminishing returns beyond 300-400 mcg in humans. Treatment cycles of 3-6 months with equal rest periods are commonly employed to maintain pituitary responsiveness.
Most research suggests using 100-300 mcg of GHRP-2 per day, split into 2-3 injections under the skin. A typical schedule would be: 100 mcg when you wake up (on an empty stomach), 100 mcg in the afternoon (preferably before exercise), and 100-200 mcg before bed. Start with lower doses to assess tolerance. Many people use it for 3-6 months, then take an equal break to keep their body responsive to its effects.
Mixing & Injection
GHRP-2 is administered via subcutaneous injection using insulin syringes, typically into the abdominal area, thigh, or upper arm. Rotate injection sites to prevent tissue damage. Reconstitute lyophilized powder with bacteriostatic water at 1 mg/mL concentration. Administer on an empty stomach for optimal absorption, waiting at least 30 minutes before eating. Timing is crucial: morning doses should be taken immediately upon waking, while evening doses should be administered 2-3 hours after dinner and immediately before sleep to capitalize on natural growth hormone pulses.
GHRP-2 is administered via subcutaneous injection using insulin syringes, typically into the abdominal area, thigh, or upper arm. Rotate injection sites to prevent tissue damage. Reconstitute lyophilized powder with bacteriostatic water at 1 mg/mL concentration. Administer on an empty stomach for optimal absorption, waiting at least 30 minutes before eating. Timing is crucial: morning doses should be taken immediately upon waking, while evening doses should be administered 2-3 hours after dinner and immediately before sleep to capitalize on natural growth hormone pulses.
Clinical Administration Guidelines
Injection Protocol
- •Subcutaneous injection 2-3 times daily
- •MANDATORY site rotation (abdomen, thigh, upper arm)
- •2-3 times daily on empty stomach
- •Empty stomach for optimal GH release
Monitoring Schedule
- •Monitor GH response and muscle gains
- •Monthly IGF-1 and growth hormone levels
- •Monthly growth hormone and metabolic panels
- •STOP if severe hypoglycemia or pituitary issues
Dosage Calculator
Medical Disclaimer
GHRP-2 is an investigational research compound not approved by the FDA for human therapeutic use. This information is for educational purposes only and should not be construed as medical advice. Any use should occur only under medical supervision in approved research settings.