Epithalon

Research protocols employ cyclic dosing: 1 µg/day SC for 5 days monthly over 6 months in mice for longevity studies (Anisimov et al., 2003), 5 µg/day IP for 10 days in rats for pineal function research (Khavinson et al., 2001), and 10 µM for 72 hours in cell culture studies for telomerase activation (Khavinson et al., 2003). All doses are reconstituted in sterile saline at 1 mg/mL concentration.

The dosing is like a monthly tune-up: mice get 1 µg daily for 5 days each month for half a year, rats get 5 µg daily for 10 days, and cells in dishes get 10 µM for 3 days. Mix it all with clean saltwater at 1 mg/mL - it's like giving cells and animals a regular anti-aging boost.

Epithalon is administered via subcutaneous (SC) or intraperitoneal (IP) injection in animal studies, reconstituted in sterile saline at 1 mg/mL under aseptic conditions. Cyclic administration protocols (5 days on, 25 days off) are commonly used to mimic physiological pulsatile release patterns. Storage at 2-8°C or -20°C in low-protein-binding vials prevents degradation. Injection timing may align with circadian rhythms for optimal pineal effects.

Epithalon is administered via subcutaneous (SC) or intraperitoneal (IP) injection in animal studies, reconstituted in sterile saline at 1 mg/mL under aseptic conditions. Cyclic administration protocols (5 days on, 25 days off) are commonly used to mimic physiological pulsatile release patterns. Storage at 2-8°C or -20°C in low-protein-binding vials prevents degradation. Injection timing may align with circadian rhythms for optimal pineal effects.

Injection Protocol

• •Subcutaneous injection in 5-day cycles
• •Rotate between abdomen, thigh, upper arm
• •Same time daily during 5-day cycles
• •Can be taken with or without food

Monitoring Schedule

• •Track biomarkers of aging and cellular health
• •Monthly comprehensive health panels
• •Quarterly telomerase activity and oxidative stress markers
• •Monitor for any unusual symptoms during cycles