AOD-9604
Human Growth Hormone Fragment 176-191
AOD-9604 is a modified fragment of human growth hormone (HGH) comprising amino acids 176-191 from the C-terminus. Developed by Metabolic Pharmaceuticals, this peptide specifically targets fat loss without the growth-promoting effects of full HGH. It stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation), making it a targeted approach for body composition improvement and weight management.
AOD-9604 Mechanism of Action
The Complete Journey: From Injection to Results
AOD-9604 represents the last 16 amino acids (176-191) of the human growth hormone molecule, specifically the region responsible for fat metabolism without growth promotion. It binds to β3-adrenergic receptors on adipocytes, activating adenylyl cyclase and increasing cyclic adenosine monophosphate (cAMP) levels. This cascade activates hormone-sensitive lipase, promoting lipolysis (fat breakdown) while simultaneously inhibiting acetyl-CoA carboxylase, reducing lipogenesis (fat formation). The peptide mimics the natural fat-burning properties of HGH without affecting growth, insulin sensitivity, or IGF-1 production.
The Injection
You inject AOD-9604 under your skin. This growth hormone fragment begins absorbing into your bloodstream.
Bloodstream Distribution
AOD-9604 travels to fat cells throughout your body, seeking out specific receptors on adipocytes (fat cells). It has a special affinity for abdominal and stubborn fat areas.
Fat Cell Activation
The peptide activates fat-burning enzymes and stimulates lipolysis (fat breakdown) without affecting muscle tissue. It specifically targets stored fat for energy.
Metabolic Enhancement
Your body's fat-burning processes ramp up significantly. AOD-9604 preserves muscle mass while specifically targeting fat tissue for breakdown.
Peak Fat Burning
Maximum fat-burning effects achieved. Your body becomes highly efficient at using stored fat for energy while preserving lean muscle mass.
Visible Results
Measurable fat loss with preserved muscle mass. Body composition improves with clearly visible changes in measurements and appearance.
How AOD-9604 Works at the Molecular Level
Scientific Mechanism
AOD-9604 represents the last 16 amino acids (176-191) of the human growth hormone molecule, specifically the region responsible for fat metabolism without growth promotion. It binds to β3-adrenergic receptors on adipocytes, activating adenylyl cyclase and increasing cyclic adenosine monophosphate (cAMP) levels. This cascade activates hormone-sensitive lipase, promoting lipolysis (fat breakdown) while simultaneously inhibiting acetyl-CoA carboxylase, reducing lipogenesis (fat formation). The peptide mimics the natural fat-burning properties of HGH without affecting growth, insulin sensitivity, or IGF-1 production.
Simple Explanation
Think of AOD-9604 as taking only the fat-burning part of growth hormone and leaving behind everything else. Growth hormone naturally burns fat, but it also affects growth, blood sugar, and can cause side effects. AOD-9604 is like extracting just the 'fat-burning instructions' from growth hormone. It tells your fat cells to break down stored fat for energy while preventing new fat from being stored. It's like having a very focused, targeted fat-burning signal without any of the complications.
The Simple Truth: Why It Works So Well
Medical Disclaimer
AOD-9604 is an investigational research compound not approved by the FDA for human therapeutic use. This information is for educational purposes only and should not be construed as medical advice. Any use should occur only under medical supervision in approved research settings.