Tirzepatide
Dual GIP and GLP-1 Receptor Agonist
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Available as FDA-approved Mounjaro® for Type 2 diabetes and Zepbound® for weight management and obstructive sleep apnea. It provides superior weight loss and glycemic control compared to single-pathway medications through its unique dual mechanism of action.
Comprehensive Dosing Guide
How to Take Tirzepatide
For Type 2 Diabetes
Starting Dose:
- 2.5 mg injected under the skin once a week.
- Note: This initial dose helps your body get used to the medication and doesn't control blood sugar.
Increasing the Dose:
- After 4 weeks, increase to 5 mg once a week.
- After another 4 weeks, you might increase to 7.5 mg once a week if needed and if you're handling it well.
Regular Dose:
- 7.5 mg once a week.
- If you need better blood sugar control and tolerate 7.5 mg, your doctor might increase it to 10 mg once a week.
- The dose can be further increased to a maximum of 15 mg once a week based on your needs and how well you tolerate the medication.
How to Take It:
- Take it on the same day every week, with or without food.
- Don't take more than one dose in a week.
- Change the injection spot each week (belly, thigh, or upper arm) to avoid skin issues.
For Weight Loss
Starting Dose:
- 2.5 mg injected under the skin once a week for the first 4 weeks.
Increasing the Dose:
- After 4 weeks, increase to 5 mg once a week for the next 4 weeks.
- After another 4 weeks, increase to 7.5 mg once a week.
- You can keep increasing by 2.5 mg every 4 weeks if needed, up to 15 mg once a week.
Regular Dose:
- 15 mg once a week, following the same schedule for increases.
How to Take It:
- Take it on the same day every week, with or without food.
- Change the injection spot each week (belly, thigh, or upper arm).
Medical Disclaimer
Tirzepatide is FDA-approved as Mounjaro® for Type 2 diabetes and Zepbound® for chronic weight management. This information is for educational purposes and should not replace consultation with healthcare providers. Individual results may vary. Prescribing information and medical supervision are required for all therapeutic uses.